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Received : 09-04-2021

Accepted : 22-04-2021

Available online : 11-11-2021

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Assessment of post-operative analgesia in modified radical mastectomy patients using surgical wound irrigation with 0.25% bupivacaine

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Original Article

Author Details : Muhammed Shafi C, Brejesh Ravi Varma*, Mangesh Shenoy, Salman Mohammed Kutty

Volume : 8, Issue : 4, Year : 2021

Article Page : 507-510

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Background: Modified Radical Mastectomy is the widely followed treatment for operable breast cancers. Among the methods used to alleviate pain, irrigation of wound with 0.25% Bupivacaine is one of the under-utilized methods with good efficiency compared to other drugs.
Objectives: To evaluate the role of local irrigation of 0.25% bupivacaine in alleviating the post-operative pain.
Materials and Methods: This observational study was conducted among 60 female patients who underwent Modified Radical Mastectomy in a tertiary care teaching hospital between January 2017 and July 2018. Thirty (30) patients were randomly allotted to control group, where the routine post-operative pain management was followed. Another 30 were randomly allotted to study group where, before closure of the wound, a 20G scalp vein set was used along the length of the incision with multiple punctures in it for continuous irrigation with 0.25% Bupivacaine. Post operatively Visual analogue scale was used to measure the pain sensation at every six hours for 24 hours. The adverse effects like pain, hematoma, wound dehiscence, infection was noted on all the post-operative days.
Results: Both the groups were similar with respect to basic parameters measured. There was a significant reduction in need for rescue analgesia in the study group. There was a significant difference in mean VAS score between both groups from 6 hour of surgery. Post-operative nausea and vomiting was significantly less in the study group.
Conclusion: Irrigation of wound with 0.25% Bupivacaine is found to reduce the pain sensation with minimal side effects without systemic compromise.

Keywords: Bupivacaine, Modified radical mastectomy, Rescue analgesia, Post-operative pain.

How to cite : Muhammed Shafi C, Varma B R, Shenoy M, Kutty S M, Assessment of post-operative analgesia in modified radical mastectomy patients using surgical wound irrigation with 0.25% bupivacaine. Indian J Clin Anaesth 2021;8(4):507-510

Copyright © 2021 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

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