Author Details :
Volume : 8, Issue : 3, Year : 2021
Article Page : 381-386
Introduction: The postoperative sore throat (POST) occurs in approximately ? 50% of individuals after general anaesthesia. An attempt is made in the present research to evaluate the efficacy of alkalinized 2% lignocaine with conventional air as cuff inflating media, in preventing POST and coughing in patients undergoing a surgical procedure under general anaesthesia.
Materials and Methods: This randomised double-blinded controlled study was conducted in sixty patients. In Group A, the endotracheal tube (ETT) cuff was filled with air, whereas in Group B, it was filled with 2% lignocaine. Coughing and POST were recorded immediately, at 1 hour, 12 hours and 24 hours. We have compared coughing, POST following tracheal extubation, and volume of inflation medium and intra-cuff pressure at the start and at the end of surgery between the two groups.
Results: The mean volume at the end of the surgery was 7.9 mL and 4.5 mL in Group A and Group B respectively (p-value = 0.001). The mean intra-cuff pressure at the end of the surgery was 32.5 cm and 19.8 cm in Group A and Group B respectively (p-value = 0.001). The percentage change in the volume at the end of the surgery was + 49.7 and -12.7% in Group A and Group B respectively (p-value = 0.001). The percentage change in the intra-cuff pressure at the end of the surgery was + 62.5 and -1.0% in Group A and Group B respectively (p-value = 0.001). The incidence of coughing at one hour postoperative was 26.7% and 3.3% in Group A and Group B respectively (p-value = 0.026).
Conclusion: The intracuff alkalinized lidocaine is useful adjunct to endotracheal intubation.
Keywords: Postoperative sore throat, Lidocaine, Air, Endotracheal tube.
How to cite : Tappe B, Patkar C, Lokare S, Phalgune D, A randomized controlled study on efficacy and safety of air versus alkalinized 2% lignocaine for inflating endotracheal tube. Indian J Clin Anaesth 2021;8(3):381-386
Copyright © 2021 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)